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Insufficient data exists to help make suitable dosing tips regarding the use of possibly propoxyphene by yourself or in combination with acetaminophen in people with hepatic or renal impairment as being a function of degree of impairment. Better plasma concentrations and/or delayed elimination may well arise in the event of impaired hepatic purpose and/or impaired renal perform (see CLINICAL PHARMACOLOGY).
The mutagenic and carcinogenic probable of propoxyphene and acetaminophen by yourself and together have not been evaluated.
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